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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5C
All Species:
22.12
Human Site:
Y165
Identified Species:
34.76
UniProt:
O60282
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60282
NP_004513.1
957
109495
Y165
E
D
K
N
R
V
P
Y
V
K
G
C
T
E
R
Chimpanzee
Pan troglodytes
XP_525938
860
98662
S143
L
A
G
S
E
K
V
S
K
T
G
A
E
G
A
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
S143
L
A
G
S
E
K
V
S
K
T
G
A
E
G
A
Dog
Lupus familis
XP_533351
955
109129
Y164
E
D
K
N
R
V
P
Y
V
K
G
C
T
E
R
Cat
Felis silvestris
Mouse
Mus musculus
P28738
956
109222
Y165
E
D
K
N
R
V
P
Y
V
K
G
C
T
E
R
Rat
Rattus norvegicus
Q6QLM7
1027
116897
F165
E
D
K
N
R
V
P
F
V
R
G
C
T
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
Y164
E
D
K
N
R
V
P
Y
V
K
G
C
T
E
R
Chicken
Gallus gallus
Q90640
1225
138905
E170
S
I
R
E
D
P
K
E
G
I
K
I
V
G
L
Frog
Xenopus laevis
Q91784
1226
138905
E169
S
I
R
E
D
P
K
E
G
I
K
I
C
G
L
Zebra Danio
Brachydanio rerio
NP_001116747
985
113653
F164
E
D
K
N
R
V
P
F
V
K
G
C
T
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
Y171
E
D
K
N
R
V
P
Y
V
K
G
A
T
E
R
Honey Bee
Apis mellifera
XP_395236
988
112484
F175
E
D
K
N
R
V
P
F
V
K
G
A
T
E
R
Nematode Worm
Caenorhab. elegans
P34540
815
91875
M125
I
F
N
H
I
Y
S
M
D
E
N
L
Q
F
H
Sea Urchin
Strong. purpuratus
P35978
1031
117504
F163
E
D
K
N
R
V
P
F
V
K
G
A
T
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
Y168
E
E
K
N
R
G
V
Y
V
K
G
L
L
E
I
Conservation
Percent
Protein Identity:
100
89.8
85.5
98.3
N.A.
98
69.8
N.A.
75.2
26.3
24.8
76.8
N.A.
62
63.2
45.3
61.4
Protein Similarity:
100
89.8
86.4
98.9
N.A.
99.1
81.6
N.A.
86.4
45.3
45.5
86.9
N.A.
77.6
77.9
61.3
74.7
P-Site Identity:
100
6.6
6.6
100
N.A.
100
86.6
N.A.
100
0
0
93.3
N.A.
93.3
86.6
0
86.6
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
100
N.A.
100
6.6
6.6
100
N.A.
93.3
93.3
13.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
31.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
52.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
0
0
0
0
0
0
0
0
34
0
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
40
7
0
0
% C
% Asp:
0
60
0
0
14
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
67
7
0
14
14
0
0
14
0
7
0
0
14
67
0
% E
% Phe:
0
7
0
0
0
0
0
27
0
0
0
0
0
7
0
% F
% Gly:
0
0
14
0
0
7
0
0
14
0
80
0
0
27
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
14
0
0
7
0
0
0
0
14
0
14
0
0
7
% I
% Lys:
0
0
67
0
0
14
14
0
14
60
14
0
0
0
0
% K
% Leu:
14
0
0
0
0
0
0
0
0
0
0
14
7
0
14
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
67
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
14
60
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
14
0
67
0
0
0
0
7
0
0
0
0
60
% R
% Ser:
14
0
0
14
0
0
7
14
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
14
0
0
60
0
0
% T
% Val:
0
0
0
0
0
60
20
0
67
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _